Gene-specific Copy Number Variation Probe-MAML2
Add to Cart
| Catalog: |
CNVFP-MAML2-10819 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (MAML2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
MAML2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to MAML2 genes. This product achieves the purpose of detection by hybridizing with the MAML2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Mastermind Like Transcriptional Coactivator 2 |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a member of the Mastermind-like family of proteins. All family members are proline and glutamine-rich, and contain a conserved basic domain that binds the ankyrin repeat domain of the intracellular domain of the Notch receptors (ICN1-4) in their N-terminus, and a transcriptional activation domain in their C-terminus. This protein binds to an extended groove that is formed by the interaction of CBF1, Suppressor of Hairless, LAG-1 (CSL) with ICN, and positively regulates Notch signaling. High levels of expression of this gene have been observed in several B cell-derived lymphomas. Translocations resulting in fusion proteins with both CRTC1 and CRTC3 have been implicated in the development of mucoepidermoid carcinomas, while a translocation event with CXCR4 has been linked with chronic lymphocytic leukemia (CLL). Copy number variation in the polyglutamine tract has been observed. [provided by RefSeq, Jan 2015] |
| Gene Symbol |
MAML2 |
| Location |
11q21 |
| Chromosome |
Chromosome11 |
| Coordinates |
This gene maps to 95711439-96076344 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-MAML2-10819-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-MAML2-10819-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-MAML2-10819-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-MAML2-10819-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-MAML2-10819-AQ |
467nm |
418nm |
|
Other Products
