Gene-specific Copy Number Variation Probe-LIMK1
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| Catalog: |
CNVFP-LIMK1-08628 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (LIMK1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
LIMK1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to LIMK1 genes. This product achieves the purpose of detection by hybridizing with the LIMK1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
LIM Domain Kinase 1 |
| Gene Summary [Provided by RefSeq] |
There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is a serine/threonine kinase that regulates actin polymerization via phosphorylation and inactivation of the actin binding factor cofilin. This protein is ubiquitously expressed during development and plays a role in many cellular processes associated with cytoskeletal structure. This protein also stimulates axon growth and may play a role in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Feb 2011] |
| Gene Symbol |
LIMK1 |
| Location |
7q11.23 |
| Chromosome |
Chromosome7 |
| Coordinates |
This gene maps to 73498106-73536855 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-LIMK1-08628-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-LIMK1-08628-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-LIMK1-08628-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-LIMK1-08628-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-LIMK1-08628-AQ |
467nm |
418nm |
|
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