Gene-specific Copy Number Variation Probe-LIG4
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| Catalog: |
CNVFP-LIG4-08643 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (LIG4). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
LIG4 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to LIG4 genes. This product achieves the purpose of detection by hybridizing with the LIG4 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
DNA Ligase 4 |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA-dependent protein kinase (DNA-PK). Both XRCC4 and DNA-PK are known to be required for NHEJ. The crystal structure of the complex formed by this protein and XRCC4 has been resolved. Defects in this gene are the cause of LIG4 syndrome. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
LIG4 |
| Location |
13q33.3 |
| Chromosome |
Chromosome13 |
| Coordinates |
This gene maps to 108859791-108870716 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-LIG4-08643-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-LIG4-08643-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-LIG4-08643-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-LIG4-08643-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-LIG4-08643-AQ |
467nm |
418nm |
|
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