Gene-specific Copy Number Variation Probe-LFNG
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Catalog: |
CNVFP-LFNG-08370 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (LFNG). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
LFNG Gene-specific copy number variation probes are mainly used to detect the copy number variation related to LFNG genes. This product achieves the purpose of detection by hybridizing with the LFNG gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
Gene Summary [Provided by RefSeq] |
This gene is a member of the fringe gene family which also includes radical and manic fringe genes. They all encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. This gene product is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150). Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009] |
Gene Symbol |
LFNG |
Location |
7p22.3 |
Chromosome |
Chromosome7 |
Coordinates |
This gene maps to 2552162-2568063 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
OR
|
CNVFP-LFNG-08370-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-LFNG-08370-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-LFNG-08370-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-LFNG-08370-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-LFNG-08370-AQ |
467nm |
418nm |
|
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