Gene-specific Copy Number Variation Probe-LEPR
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Catalog: |
CNVFP-LEPR-08377 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (LEPR). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
LEPR Gene-specific copy number variation probes are mainly used to detect the copy number variation related to LEPR genes. This product achieves the purpose of detection by hybridizing with the LEPR gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Leptin Receptor |
Gene Summary [Provided by RefSeq] |
The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010] |
Gene Symbol |
LEPR |
Location |
1p31.3 |
Chromosome |
Chromosome1 |
Coordinates |
This gene maps to 65886334-66103176 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-LEPR-08377-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-LEPR-08377-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-LEPR-08377-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-LEPR-08377-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-LEPR-08377-AQ |
467nm |
418nm |
|
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