Gene-specific Copy Number Variation Probe-LEP
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| Catalog: |
CNVFP-LEP-08378 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (LEP). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
LEP Gene-specific copy number variation probes are mainly used to detect the copy number variation related to LEP genes. This product achieves the purpose of detection by hybridizing with the LEP gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Leptin |
| Gene Summary [Provided by RefSeq] |
This gene encodes a protein that is secreted by white adipocytes into the circulation and plays a major role in the regulation of energy homeostasis. Circulating leptin binds to the leptin receptor in the brain, which activates downstream signaling pathways that inhibit feeding and promote energy expenditure. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis, reproduction, bone formation and wound healing. Mutations in this gene and its regulatory regions cause severe obesity and morbid obesity with hypogonadism in human patients. A mutation in this gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq, Aug 2017] |
| Gene Symbol |
LEP |
| Location |
7q32.1 |
| Chromosome |
Chromosome7 |
| Coordinates |
This gene maps to 127881330-127897682 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-LEP-08378-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-LEP-08378-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-LEP-08378-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-LEP-08378-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-LEP-08378-AQ |
467nm |
418nm |
|
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