Gene-specific Copy Number Variation Probe-LATS1
Add to Cart
| Catalog: |
CNVFP-LATS1-08460 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (LATS1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
LATS1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to LATS1 genes. This product achieves the purpose of detection by hybridizing with the LATS1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Large Tumor Suppressor Kinase 1 |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell-cycle dependent manner, with late prophase phosphorylation remaining through metaphase. The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative regulator of CDC2/cyclin A. In addition, the C-terminal kinase domain binds to its own N-terminal region, suggesting potential negative regulation through interference with complex formation via intramolecular binding. Biochemical and genetic data suggest a role as a tumor suppressor. This is supported by studies in knockout mice showing development of soft-tissue sarcomas, ovarian stromal cell tumors and a high sensitivity to carcinogenic treatments. [provided by RefSeq, Apr 2017] |
| Gene Symbol |
LATS1 |
| Location |
6q25.1 |
| Chromosome |
Chromosome6 |
| Coordinates |
This gene maps to 149982050-150039392 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-LATS1-08460-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-LATS1-08460-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-LATS1-08460-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-LATS1-08460-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-LATS1-08460-AQ |
467nm |
418nm |
|
Other Products
