Gene-specific Copy Number Variation Probe-KRT6A
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| Catalog: |
CNVFP-KRT6A-08168 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (KRT6A). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
KRT6A Gene-specific copy number variation probes are mainly used to detect the copy number variation related to KRT6A genes. This product achieves the purpose of detection by hybridizing with the KRT6A gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Keratin 6A |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. In addition, peptides from the C-terminal region of the protein have antimicrobial activity against bacterial pathogens. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Oct 2014] |
| Gene Symbol |
KRT6A |
| Location |
12q13.13 |
| Chromosome |
Chromosome12 |
| Coordinates |
This gene maps to 52880957-52887181 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-KRT6A-08168-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-KRT6A-08168-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-KRT6A-08168-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-KRT6A-08168-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-KRT6A-08168-AQ |
467nm |
418nm |
|
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