Gene-specific Copy Number Variation Probe-KPNB1
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| Catalog: |
CNVFP-KPNB1-08243 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (KPNB1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
KPNB1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to KPNB1 genes. This product achieves the purpose of detection by hybridizing with the KPNB1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Karyopherin Subunit Beta 1 |
| Gene Summary [Provided by RefSeq] |
Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013] |
| Gene Symbol |
KPNB1 |
| Location |
17q21.32 |
| Chromosome |
Chromosome17 |
| Coordinates |
This gene maps to 45727274-45761004 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-KPNB1-08243-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-KPNB1-08243-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-KPNB1-08243-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-KPNB1-08243-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-KPNB1-08243-AQ |
467nm |
418nm |
|
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