Gene-specific Copy Number Variation Probe-KPNA2
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| Catalog: |
CNVFP-KPNA2-08214 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (KPNA2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
KPNA2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to KPNA2 genes. This product achieves the purpose of detection by hybridizing with the KPNA2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Karyopherin Subunit Alpha 2 |
| Gene Summary [Provided by RefSeq] |
The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] |
| Gene Symbol |
KPNA2 |
| Location |
17q24.2 |
| Chromosome |
Chromosome17 |
| Coordinates |
This gene maps to 66031847-66042970 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-KPNA2-08214-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-KPNA2-08214-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-KPNA2-08214-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-KPNA2-08214-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-KPNA2-08214-AQ |
467nm |
418nm |
|
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