Gene-specific Copy Number Variation Probe-KMT2A
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| Catalog: |
CNVFP-KMT2A-08228 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (KMT2A). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
KMT2A Gene-specific copy number variation probes are mainly used to detect the copy number variation related to KMT2A genes. This product achieves the purpose of detection by hybridizing with the KMT2A gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Lysine Methyltransferase 2A |
| Gene Summary [Provided by RefSeq] |
This gene encodes a transcriptional coactivator that plays an essential role in regulating gene expression during early development and hematopoiesis. The encoded protein contains multiple conserved functional domains. One of these domains, the SET domain, is responsible for its histone H3 lysine 4 (H3K4) methyltransferase activity which mediates chromatin modifications associated with epigenetic transcriptional activation. This protein is processed by the enzyme Taspase 1 into two fragments, MLL-C and MLL-N. These fragments reassociate and further assemble into different multiprotein complexes that regulate the transcription of specific target genes, including many of the HOX genes. Multiple chromosomal translocations involving this gene are the cause of certain acute lymphoid leukemias and acute myeloid leukemias. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2010] |
| Gene Symbol |
KMT2A |
| Location |
11q23.3 |
| Chromosome |
Chromosome11 |
| Coordinates |
This gene maps to 118436489-118526831 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-KMT2A-08228-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-KMT2A-08228-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-KMT2A-08228-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-KMT2A-08228-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-KMT2A-08228-AQ |
467nm |
418nm |
|
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