Gene-specific Copy Number Variation Probe-KLRK1
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| Catalog: |
CNVFP-KLRK1-08302 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (KLRK1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
KLRK1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to KLRK1 genes. This product achieves the purpose of detection by hybridizing with the KLRK1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Killer Cell Lectin Like Receptor K1 |
| Gene Summary [Provided by RefSeq] |
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. This gene encodes a member of the NKG2 family. The encoded transmembrane protein is characterized by a type II membrane orientation (has an extracellular C terminus) and the presence of a C-type lectin domain. It binds to a diverse family of ligands that include MHC class I chain-related A and B proteins and UL-16 binding proteins, where ligand-receptor interactions can result in the activation of NK and T cells. The surface expression of these ligands is important for the recognition of stressed cells by the immune system, and thus this protein and its ligands are therapeutic targets for the treatment of immune diseases and cancers. Read-through transcription exists between this gene and the upstream KLRC4 (killer cell lectin-like receptor subfamily C, member 4) family member in the same cluster. [provided by RefSeq, Dec 2010] |
| Gene Symbol |
KLRK1 |
| Location |
12p13.2 |
| Chromosome |
Chromosome12 |
| Coordinates |
This gene maps to 10524951-10542653 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-KLRK1-08302-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-KLRK1-08302-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-KLRK1-08302-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-KLRK1-08302-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-KLRK1-08302-AQ |
467nm |
418nm |
|
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