Gene-specific Copy Number Variation Probe-KISS1
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Catalog: |
CNVFP-KISS1-07941 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (KISS1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
KISS1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to KISS1 genes. This product achieves the purpose of detection by hybridizing with the KISS1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
KiSS-1 Metastasis-suppressor |
Gene Summary [Provided by RefSeq] |
This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH nuerons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. [provided by RefSeq, Mar 2012] |
Gene Symbol |
KISS1 |
Location |
1q32.1 |
Chromosome |
Chromosome1 |
Coordinates |
This gene maps to 204159468-204165619 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-KISS1-07941-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-KISS1-07941-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-KISS1-07941-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-KISS1-07941-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-KISS1-07941-AQ |
467nm |
418nm |
|
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