Gene-specific Copy Number Variation Probe-KIR2DL5B
Add to Cart
| Catalog: |
CNVFP-KIR2DL5B-07936 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (KIR2DL5B). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
KIR2DL5B Gene-specific copy number variation probes are mainly used to detect the copy number variation related to KIR2DL5B genes. This product achieves the purpose of detection by hybridizing with the KIR2DL5B gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Killer Cell Immunoglobulin Like Receptor, Two Ig Domains And Long Cytoplasmic Tail 5B |
| Gene Summary [Provided by RefSeq] |
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
KIR2DL5B |
| Location |
19p13.3 |
| Chromosome |
Chromosome19_gl000209_random |
| Coordinates |
This gene maps to 86745-96246 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-KIR2DL5B-07936-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-KIR2DL5B-07936-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-KIR2DL5B-07936-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-KIR2DL5B-07936-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-KIR2DL5B-07936-AQ |
467nm |
418nm |
|
Other Products
