Gene-specific Copy Number Variation Probe-ITGA8
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| Catalog: |
CNVFP-ITGA8-07666 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (ITGA8). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
ITGA8 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to ITGA8 genes. This product achieves the purpose of detection by hybridizing with the ITGA8 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Integrin Subunit Alpha 8 |
| Gene Summary [Provided by RefSeq] |
Integrins are heterodimeric transmembrane receptor proteins that mediate numerous cellular processes including cell adhesion, cytoskeletal rearrangement, and activation of cell signaling pathways. Integrins are composed of alpha and beta subunits. This gene encodes the alpha 8 subunit of the heterodimeric integrin alpha8beta1 protein. The encoded protein is a single-pass type 1 membrane protein that contains multiple FG-GAP repeats. This repeat is predicted to fold into a beta propeller structure. This gene regulates the recruitment of mesenchymal cells into epithelial structures, mediates cell-cell interactions, and regulates neurite outgrowth of sensory and motor neurons. The integrin alpha8beta1 protein thus plays an important role in wound-healing and organogenesis. Mutations in this gene have been associated with renal hypodysplasia/aplasia-1 (RHDA1) and with several animal models of chronic kidney disease. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2014] |
| Gene Symbol |
ITGA8 |
| Location |
10p13 |
| Chromosome |
Chromosome10 |
| Coordinates |
This gene maps to 15559087-15761770 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-ITGA8-07666-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-ITGA8-07666-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-ITGA8-07666-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-ITGA8-07666-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-ITGA8-07666-AQ |
467nm |
418nm |
|
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