Gene-specific Copy Number Variation Probe-INPP5D
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| Catalog: |
CNVFP-INPP5D-07424 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (INPP5D). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
INPP5D Gene-specific copy number variation probes are mainly used to detect the copy number variation related to INPP5D genes. This product achieves the purpose of detection by hybridizing with the INPP5D gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Inositol Polyphosphate-5-phosphatase B |
| Gene Summary [Provided by RefSeq] |
This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. The protein is also partly localized to the nucleus, where it may be involved in nuclear inositol phosphate signaling processes. Overall, the protein functions as a negative regulator of myeloid cell proliferation and survival. Mutations in this gene are associated with defects and cancers of the immune system. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2014] |
| Gene Symbol |
INPP5D |
| Location |
2q37.1 |
| Chromosome |
Chromosome2 |
| Coordinates |
This gene maps to 233925035-234116549 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-INPP5D-07424-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-INPP5D-07424-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-INPP5D-07424-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-INPP5D-07424-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-INPP5D-07424-AQ |
467nm |
418nm |
|
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