Gene-specific Copy Number Variation Probe-IMPA1
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| Catalog: |
CNVFP-IMPA1-07441 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (IMPA1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
IMPA1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to IMPA1 genes. This product achieves the purpose of detection by hybridizing with the IMPA1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Inositol Monophosphatase 1 |
| Gene Summary [Provided by RefSeq] |
This gene encodes an enzyme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1,4,5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13. [provided by RefSeq, Dec 2014] |
| Gene Symbol |
IMPA1 |
| Location |
8q21.13 |
| Chromosome |
Chromosome8 |
| Coordinates |
This gene maps to 82569150-82598589 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-IMPA1-07441-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-IMPA1-07441-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-IMPA1-07441-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-IMPA1-07441-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-IMPA1-07441-AQ |
467nm |
418nm |
|
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