Gene-specific Copy Number Variation Probe-IL4R
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| Catalog: |
CNVFP-IL4R-07461 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (IL4R). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
IL4R Gene-specific copy number variation probes are mainly used to detect the copy number variation related to IL4R genes. This product achieves the purpose of detection by hybridizing with the IL4R gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Interleukin 4 Receptor |
| Gene Summary [Provided by RefSeq] |
This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012] |
| Gene Symbol |
IL4R |
| Location |
16p12.1 |
| Chromosome |
Chromosome16 |
| Coordinates |
This gene maps to 27325250-27376099 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-IL4R-07461-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-IL4R-07461-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-IL4R-07461-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-IL4R-07461-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-IL4R-07461-AQ |
467nm |
418nm |
|
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