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Gene-specific Copy Number Variation Probe-IL12RB1

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Catalog: CNVFP-IL12RB1-07520
Classification: Copy Number Variation
Description: Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (IL12RB1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services.
Application: IL12RB1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to IL12RB1 genes. This product achieves the purpose of detection by hybridizing with the IL12RB1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH.
Category: Copy Number Variation
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name Interleukin 12 Receptor Subunit Beta 1
Gene Summary [Provided by RefSeq] The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Gene Symbol IL12RB1
Location 19p13.11
Chromosome Chromosome19
Coordinates This gene maps to 18170370-18197697 in GRCh37 coordinates.
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 OR CNVFP-IL12RB1-07520-OR 573nm 548nm
2 RE CNVFP-IL12RB1-07520-RE 599nm 580nm
3 GO CNVFP-IL12RB1-07520-GO 551nm 525nm
4 GR CNVFP-IL12RB1-07520-GR 515nm 491nm
5 AQ CNVFP-IL12RB1-07520-AQ 467nm 418nm

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