Gene-specific Copy Number Variation Probe-IL12B
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| Catalog: |
CNVFP-IL12B-07522 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (IL12B). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
IL12B Gene-specific copy number variation probes are mainly used to detect the copy number variation related to IL12B genes. This product achieves the purpose of detection by hybridizing with the IL12B gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Interleukin 12B |
| Gene Summary [Provided by RefSeq] |
This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
IL12B |
| Location |
5q33.3 |
| Chromosome |
Chromosome5 |
| Coordinates |
This gene maps to 158741790-158757481 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-IL12B-07522-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-IL12B-07522-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-IL12B-07522-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-IL12B-07522-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-IL12B-07522-AQ |
467nm |
418nm |
|
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