Gene-specific Copy Number Variation Probe-IL10
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| Catalog: |
CNVFP-IL10-07527 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (IL10). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
IL10 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to IL10 genes. This product achieves the purpose of detection by hybridizing with the IL10 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Interleukin 10 |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011] |
| Gene Symbol |
IL10 |
| Location |
1q32.1 |
| Chromosome |
Chromosome1 |
| Coordinates |
This gene maps to 206940947-206945839 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-IL10-07527-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-IL10-07527-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-IL10-07527-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-IL10-07527-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-IL10-07527-AQ |
467nm |
418nm |
|
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