Gene-specific Copy Number Variation Probe-IGL
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Catalog: |
CNVFP-IGL-07235 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (IGL). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
IGL Gene-specific copy number variation probes are mainly used to detect the copy number variation related to IGL genes. This product achieves the purpose of detection by hybridizing with the IGL gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Immunoglobulin Lambda Locus |
Gene Summary [Provided by RefSeq] |
Immunoglobulins recognize foreign antigens and initiate immune responses such as phagocytosis and the complement system. Each immunoglobulin molecule consists of two identical heavy chains and two identical light chains. There are two classes of light chains, kappa and lambda. This region represents the germline organization of the lambda light chain locus. The locus includes V (variable), J (joining), and C (constant) segments. During B cell development, a recombination event at the DNA level joins a single V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase, and by somatic hypermutation, which occurs during B cell maturation in the spleen and lymph nodes. Several V segments and three C segments are known to be incapable of encoding a protein and are considered pseudogenes. The locus also includes several non-immunoglobulin genes, many of which are pseudogenes or are predicted by automated computational analysis or homology to other species. [provided by RefSeq, Jul 2008] |
Gene Symbol |
IGL |
Location |
22q11.22 |
Chromosome |
Chromosome22 |
Coordinates |
This gene maps to 22026075-22922912 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
OR
|
CNVFP-IGL-07235-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-IGL-07235-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-IGL-07235-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-IGL-07235-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-IGL-07235-AQ |
467nm |
418nm |
|
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