Gene-specific Copy Number Variation Probe-IDE
Add to Cart
Catalog: |
CNVFP-IDE-07132 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (IDE). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
IDE Gene-specific copy number variation probes are mainly used to detect the copy number variation related to IDE genes. This product achieves the purpose of detection by hybridizing with the IDE gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Insulin Degrading Enzyme |
Gene Summary [Provided by RefSeq] |
This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.[provided by RefSeq, Sep 2009] |
Gene Symbol |
IDE |
Location |
10q23.33 |
Chromosome |
Chromosome10 |
Coordinates |
This gene maps to 94211440-94333852 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
OR
|
CNVFP-IDE-07132-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-IDE-07132-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-IDE-07132-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-IDE-07132-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-IDE-07132-AQ |
467nm |
418nm |
|
Other Products