Gene-specific Copy Number Variation Probe-HYOU1
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Catalog: |
CNVFP-HYOU1-07177 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (HYOU1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
HYOU1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to HYOU1 genes. This product achieves the purpose of detection by hybridizing with the HYOU1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Hypoxia Up-regulated 1 |
Gene Summary [Provided by RefSeq] |
The protein encoded by this gene belongs to the heat shock protein 70 family. This gene uses alternative transcription start sites. A cis-acting segment found in the 5' UTR is involved in stress-dependent induction, resulting in the accumulation of this protein in the endoplasmic reticulum (ER) under hypoxic conditions. The protein encoded by this gene is thought to play an important role in protein folding and secretion in the ER. Since suppression of the protein is associated with accelerated apoptosis, it is also suggested to have an important cytoprotective role in hypoxia-induced cellular perturbation. This protein has been shown to be up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness. This gene also has an alternative translation initiation site, resulting in a protein that lacks the N-terminal signal peptide. This signal peptide-lacking protein, which is only 3 amino acids shorter than the mature protein in the ER, is thought to have a housekeeping function in the cytosol. In rat, this protein localizes to both the ER by a carboxy-terminal peptide sequence and to mitochondria by an amino-terminal targeting signal. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] |
Gene Symbol |
HYOU1 |
Location |
11q23.3 |
Chromosome |
Chromosome11 |
Coordinates |
This gene maps to 118914895-118927925 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
OR
|
CNVFP-HYOU1-07177-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-HYOU1-07177-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-HYOU1-07177-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-HYOU1-07177-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-HYOU1-07177-AQ |
467nm |
418nm |
|
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