Gene-specific Copy Number Variation Probe-HSPG2
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| Catalog: |
CNVFP-HSPG2-06886 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (HSPG2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
HSPG2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to HSPG2 genes. This product achieves the purpose of detection by hybridizing with the HSPG2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Heparan Sulfate Proteoglycan 2 |
| Gene Summary [Provided by RefSeq] |
This gene encodes the perlecan protein, which consists of a core protein to which three long chains of glycosaminoglycans (heparan sulfate or chondroitin sulfate) are attached. The perlecan protein is a large multidomain proteoglycan that binds to and cross-links many extracellular matrix components and cell-surface molecules. It has been shown that this protein interacts with laminin, prolargin, collagen type IV, FGFBP1, FBLN2, FGF7 and transthyretin, etc., and it plays essential roles in multiple biological activities. Perlecan is a key component of the vascular extracellular matrix, where it helps to maintain the endothelial barrier function. It is a potent inhibitor of smooth muscle cell proliferation and is thus thought to help maintain vascular homeostasis. It can also promote growth factor (e.g., FGF2) activity and thus stimulate endothelial growth and re-generation. It is a major component of basement membranes, where it is involved in the stabilization of other molecules as well as being involved with glomerular permeability to macromolecules and cell adhesion. Mutations in this gene cause Schwartz-Jampel syndrome type 1, Silverman-Handmaker type of dyssegmental dysplasia, and tardive dyskinesia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014] |
| Gene Symbol |
HSPG2 |
| Location |
1p36.12 |
| Chromosome |
Chromosome1 |
| Coordinates |
This gene maps to 22148736-22263750 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-HSPG2-06886-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-HSPG2-06886-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-HSPG2-06886-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-HSPG2-06886-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-HSPG2-06886-AQ |
467nm |
418nm |
|
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