Gene-specific Copy Number Variation Probe-HSD17B1
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| Catalog: |
CNVFP-HSD17B1-06925 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (HSD17B1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
HSD17B1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to HSD17B1 genes. This product achieves the purpose of detection by hybridizing with the HSD17B1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Hydroxysteroid 17-beta Dehydrogenase 1 |
| Gene Summary [Provided by RefSeq] |
This gene encodes a member of the 17beta-hydroxysteroid dehydrogenase family of short-chain dehydrogenases/reductases. It has a dual function in estrogen activation and androgen inactivation and plays a major role in establishing the estrogen E2 concentration gradient between serum and peripheral tissues. The encoded protein catalyzes the last step in estrogen activation, using NADPH to convert estrogens E1 and E2 and androgens like 4-androstenedione, to testosterone. It has an N-terminal short-chain dehydrogenase domain with a cofactor binding site, and a narrow, hydrophobic C-terminal domain with a steroid substrate binding site. This gene is expressed primarily in the placenta and ovarian granulosa cells, and to a lesser extent, in the endometrium, adipose tissue, and prostate. Polymorphisms in this gene have been linked to breast and prostate cancer. A pseudogene of this gene has been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016] |
| Gene Symbol |
HSD17B1 |
| Location |
17q21.2 |
| Chromosome |
Chromosome17 |
| Coordinates |
This gene maps to 40703983-40707232 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-HSD17B1-06925-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-HSD17B1-06925-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-HSD17B1-06925-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-HSD17B1-06925-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-HSD17B1-06925-AQ |
467nm |
418nm |
|
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