Gene-specific Copy Number Variation Probe-HSD11B2
Add to Cart
| Catalog: |
CNVFP-HSD11B2-06926 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (HSD11B2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
HSD11B2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to HSD11B2 genes. This product achieves the purpose of detection by hybridizing with the HSD11B2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Hydroxysteroid 11-beta Dehydrogenase 2 |
| Gene Summary [Provided by RefSeq] |
There are at least two isozymes of the corticosteroid 11-beta-dehydrogenase, a microsomal enzyme complex responsible for the interconversion of cortisol and cortisone. The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities. The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity. In aldosterone-selective epithelial tissues such as the kidney, the type II isozyme catalyzes the glucocorticoid cortisol to the inactive metabolite cortisone, thus preventing illicit activation of the mineralocorticoid receptor. In tissues that do not express the mineralocorticoid receptor, such as the placenta and testis, it protects cells from the growth-inhibiting and/or pro-apoptotic effects of cortisol, particularly during embryonic development. Mutations in this gene cause the syndrome of apparent mineralocorticoid excess and hypertension. [provided by RefSeq, Feb 2010] |
| Gene Symbol |
HSD11B2 |
| Location |
16q22.1 |
| Chromosome |
Chromosome16 |
| Coordinates |
This gene maps to 67465035-67471454 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-HSD11B2-06926-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-HSD11B2-06926-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-HSD11B2-06926-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-HSD11B2-06926-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-HSD11B2-06926-AQ |
467nm |
418nm |
|
Other Products
