Gene-specific Copy Number Variation Probe-HOGA1
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| Catalog: |
CNVFP-HOGA1-07059 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (HOGA1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
HOGA1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to HOGA1 genes. This product achieves the purpose of detection by hybridizing with the HOGA1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
4-hydroxy-2-oxoglutarate Aldolase 1 |
| Gene Summary [Provided by RefSeq] |
The authors of PMID:20797690 cloned this gene while searching for genes in a region of chromosome 10 linked to primary hyperoxalurea type III. They noted that even though the encoded protein has been described as a mitochondrial dihydrodipicolinate synthase-like enzyme, it shares little homology with E. coli dihydrodipicolinate synthase (Dhdps), particularly in the putative substrate-binding region. Moreover, neither lysine biosynthesis nor sialic acid metabolism, for which Dhdps is responsible, occurs in vertebrate mitochondria. They propose that this gene encodes mitochondrial 4-hydroxyl-2-oxoglutarate aldolase (EC 4.1.3.16), which catalyzes the final step in the metabolic pathway of hydroxyproline, releasing glyoxylate and pyruvate. This gene is predominantly expressed in the liver and kidney, and mutations in this gene are found in patients with primary hyperoxalurea type III. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Nov 2010] |
| Gene Symbol |
HOGA1 |
| Location |
10q24.2 |
| Chromosome |
Chromosome10 |
| Coordinates |
This gene maps to 99344101-99372555 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-HOGA1-07059-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-HOGA1-07059-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-HOGA1-07059-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-HOGA1-07059-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-HOGA1-07059-AQ |
467nm |
418nm |
|
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