Gene-specific Copy Number Variation Probe-HLA-F

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Catalog:	CNVFP-HLA-F-06785
Classification:	Copy Number Variation
Description:	Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (HLA-F). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services.
Application:	HLA-F Gene-specific copy number variation probes are mainly used to detect the copy number variation related to HLA-F genes. This product achieves the purpose of detection by hybridizing with the HLA-F gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH.
Quantity:	20 Tests
Probe Kits Volume (µL):	40 μL
Hybridization Solution (µL):	200 μL
Turnaround Time:	7-10 Business Days
Shipping Time:	1-2 Day Expedited Shipping
Shipping Conditions:	-20℃
Storage Conditions:	Store at -20℃ and avoid light;

Gene Name	Major Histocompatibility Complex, Class I, F
Gene Summary [Provided by RefSeq]	This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain. [provided by RefSeq, Jul 2008]
Gene Symbol	HLA-F
Location	6p22.1
Chromosome	Chromosome6_mcf_hap5
Coordinates	This gene maps to 991650-1359214 in GRCh37 coordinates.
Species	Human

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