Gene-specific Copy Number Variation Probe-HLA-E
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Catalog: |
CNVFP-HLA-E-06787 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (HLA-E). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
HLA-E Gene-specific copy number variation probes are mainly used to detect the copy number variation related to HLA-E genes. This product achieves the purpose of detection by hybridizing with the HLA-E gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Major Histocompatibility Complex, Class I, E |
Gene Summary [Provided by RefSeq] |
HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. [provided by RefSeq, Jul 2008] |
Gene Symbol |
HLA-E |
Location |
6p22.1 |
Chromosome |
Chromosome6_cox_hap2 |
Coordinates |
This gene maps to 1969246-1974046 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
OR
|
CNVFP-HLA-E-06787-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-HLA-E-06787-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-HLA-E-06787-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-HLA-E-06787-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-HLA-E-06787-AQ |
467nm |
418nm |
|
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