Gene-specific Copy Number Variation Probe-HLA-DRA
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| Catalog: |
CNVFP-HLA-DRA-06792 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (HLA-DRA). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
HLA-DRA Gene-specific copy number variation probes are mainly used to detect the copy number variation related to HLA-DRA genes. This product achieves the purpose of detection by hybridizing with the HLA-DRA gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Major Histocompatibility Complex, Class II, DR Alpha |
| Gene Summary [Provided by RefSeq] |
HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
HLA-DRA |
| Location |
6p21.32 |
| Chromosome |
Chromosome6_mann_hap4 |
| Coordinates |
This gene maps to 3749678-3754894 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-HLA-DRA-06792-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-HLA-DRA-06792-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-HLA-DRA-06792-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-HLA-DRA-06792-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-HLA-DRA-06792-AQ |
467nm |
418nm |
|
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