Gene-specific Copy Number Variation Probe-HLA-DQB2
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| Catalog: |
CNVFP-HLA-DQB2-06795 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (HLA-DQB2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
HLA-DQB2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to HLA-DQB2 genes. This product achieves the purpose of detection by hybridizing with the HLA-DQB2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Major Histocompatibility Complex, Class II, DQ Beta 2 |
| Gene Summary [Provided by RefSeq] |
HLA-DQB2 belongs to the family of HLA class II beta chain paralogs. Class II molecules are heterodimers consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. They play a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). Polymorphisms in the alpha and beta chains specify the peptide binding specificity, and typing for these polymorphisms is routinely done for bone marrow transplantation. However this gene, HLA-DQB2, is not routinely typed, as it is not thought to have an effect on transplantation. There is conflicting evidence in the literature and public sequence databases for the protein-coding capacity of HLA-DQB2. Because there is evidence of transcription and an intact ORF, HLA-DQB2 is represented in Entrez Gene and in RefSeq as a protein-coding locus. [provided by RefSeq, Oct 2010] |
| Gene Symbol |
HLA-DQB2 |
| Location |
6p21.32 |
| Chromosome |
Chromosome6_qbl_hap6 |
| Coordinates |
This gene maps to 3955994-3963453 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-HLA-DQB2-06795-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-HLA-DQB2-06795-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-HLA-DQB2-06795-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-HLA-DQB2-06795-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-HLA-DQB2-06795-AQ |
467nm |
418nm |
|
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