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Gene-specific Copy Number Variation Probe-HLA-DPB1

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Catalog: CNVFP-HLA-DPB1-06761
Classification: Copy Number Variation
Description: Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (HLA-DPB1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services.
Application: HLA-DPB1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to HLA-DPB1 genes. This product achieves the purpose of detection by hybridizing with the HLA-DPB1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH.
Category: Copy Number Variation
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name Major Histocompatibility Complex, Class II, DP Beta 1
Gene Summary [Provided by RefSeq] HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq, Jul 2008]
Gene Symbol HLA-DPB1
Location 6p21.32
Chromosome Chromosome6_mann_hap4
Coordinates This gene maps to 4501242-4515019 in GRCh37 coordinates.
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 OR CNVFP-HLA-DPB1-06761-OR 573nm 548nm
2 RE CNVFP-HLA-DPB1-06761-RE 599nm 580nm
3 GO CNVFP-HLA-DPB1-06761-GO 551nm 525nm
4 GR CNVFP-HLA-DPB1-06761-GR 515nm 491nm
5 AQ CNVFP-HLA-DPB1-06761-AQ 467nm 418nm

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