Gene-specific Copy Number Variation Probe-HLA-DOB
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| Catalog: |
CNVFP-HLA-DOB-06766 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (HLA-DOB). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
HLA-DOB Gene-specific copy number variation probes are mainly used to detect the copy number variation related to HLA-DOB genes. This product achieves the purpose of detection by hybridizing with the HLA-DOB gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Major Histocompatibility Complex, Class II, DO Beta |
| Gene Summary [Provided by RefSeq] |
HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
HLA-DOB |
| Location |
6p21.32 |
| Chromosome |
Chromosome6_ssto_hap7 |
| Coordinates |
This gene maps to 4211472-4215758 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-HLA-DOB-06766-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-HLA-DOB-06766-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-HLA-DOB-06766-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-HLA-DOB-06766-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-HLA-DOB-06766-AQ |
467nm |
418nm |
|
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