Gene-specific Copy Number Variation Probe-HIKESHI
Add to Cart
| Catalog: |
CNVFP-HIKESHI-06556 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (HIKESHI). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
HIKESHI Gene-specific copy number variation probes are mainly used to detect the copy number variation related to HIKESHI genes. This product achieves the purpose of detection by hybridizing with the HIKESHI gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Hikeshi, Heat Shock Protein Nuclear Import Factor |
| Gene Summary [Provided by RefSeq] |
This gene encodes an evolutionarily conserved nuclear transport receptor that mediates heat-shock-induced nuclear import of 70 kDa heat-shock proteins (Hsp70s) through interactions with FG-nucleoporins. The protein mediates transport of the ATP form but not the ADP form of Hsp70 proteins under conditions of heat shock stress. Structural analyses demonstrate that the protein forms an asymmetric homodimer and that the N-terminal domain consists of a jelly-roll/beta-sandwich fold structure that contains hydrophobic pockets involved in FG-nucleoporin recognition. Reduction of RNA expression levels in HeLa cells using small interfering RNAs results in inhibition of heat shock-induced nuclear accumulation of Hsp70s, indicating a role for this gene in regulation of Hsp70 nuclear import during heat shock stress. [provided by RefSeq, Apr 2016] |
| Gene Symbol |
HIKESHI |
| Location |
11q14.2 |
| Chromosome |
Chromosome11 |
| Coordinates |
This gene maps to 86302210-86345942 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-HIKESHI-06556-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-HIKESHI-06556-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-HIKESHI-06556-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-HIKESHI-06556-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-HIKESHI-06556-AQ |
467nm |
418nm |
|
Other Products
