Gene-specific Copy Number Variation Probe-HFE2
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| Catalog: |
CNVFP-HFE2-06547 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (HFE2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
HFE2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to HFE2 genes. This product achieves the purpose of detection by hybridizing with the HFE2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Hemochromatosis Type 2 (juvenile) |
| Gene Summary [Provided by RefSeq] |
The product of this gene is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Two uORFs in the 5' UTR negatively regulate the expression and activity of the encoded protein. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH). JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30. [provided by RefSeq, Oct 2015] |
| Gene Symbol |
HFE2 |
| Location |
1q21.1 |
| Chromosome |
Chromosome1 |
| Coordinates |
This gene maps to 145413190-145417545 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-HFE2-06547-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-HFE2-06547-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-HFE2-06547-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-HFE2-06547-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-HFE2-06547-AQ |
467nm |
418nm |
|
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