Gene-specific Copy Number Variation Probe-HEXB
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| Catalog: |
CNVFP-HEXB-06593 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (HEXB). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
HEXB Gene-specific copy number variation probes are mainly used to detect the copy number variation related to HEXB genes. This product achieves the purpose of detection by hybridizing with the HEXB gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Hexosaminidase Subunit Beta |
| Gene Summary [Provided by RefSeq] |
Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014] |
| Gene Symbol |
HEXB |
| Location |
5q13.3 |
| Chromosome |
Chromosome5 |
| Coordinates |
This gene maps to 73980968-74017113 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-HEXB-06593-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-HEXB-06593-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-HEXB-06593-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-HEXB-06593-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-HEXB-06593-AQ |
467nm |
418nm |
|
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