Gene-specific Copy Number Variation Probe-HAAO
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| Catalog: |
CNVFP-HAAO-06370 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (HAAO). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
HAAO Gene-specific copy number variation probes are mainly used to detect the copy number variation related to HAAO genes. This product achieves the purpose of detection by hybridizing with the HAAO gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
3-hydroxyanthranilate 3,4-dioxygenase |
| Gene Summary [Provided by RefSeq] |
3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
HAAO |
| Location |
2p21 |
| Chromosome |
Chromosome2 |
| Coordinates |
This gene maps to 42994228-43019751 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-HAAO-06370-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-HAAO-06370-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-HAAO-06370-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-HAAO-06370-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-HAAO-06370-AQ |
467nm |
418nm |
|
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