Gene-specific Copy Number Variation Probe-GSAP
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| Catalog: |
CNVFP-GSAP-06335 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (GSAP). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
GSAP Gene-specific copy number variation probes are mainly used to detect the copy number variation related to GSAP genes. This product achieves the purpose of detection by hybridizing with the GSAP gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Gamma-secretase Activating Protein |
| Gene Summary [Provided by RefSeq] |
Accumulation of neurotoxic amyloid-beta is a major hallmark of Alzheimer disease (AD; MIM 104300). Formation of amyloid-beta is catalyzed by gamma-secretase (see PSEN1; MIM 104311), a protease with numerous substrates. PION, or GSAP, selectively increases amyloid-beta production through a mechanism involving its interaction with both gamma-secretase and its substrate, the amyloid-beta precursor protein (APP; MIM 104760) C-terminal fragment (APP-CTF) (He et al., 2010 [PubMed 20811458]).[supplied by OMIM, Nov 2010] |
| Gene Symbol |
GSAP |
| Location |
7q11.23 |
| Chromosome |
Chromosome7 |
| Coordinates |
This gene maps to 77416428-77310750 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-GSAP-06335-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-GSAP-06335-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-GSAP-06335-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-GSAP-06335-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-GSAP-06335-AQ |
467nm |
418nm |
|
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