Gene-specific Copy Number Variation Probe-GRN
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| Catalog: |
CNVFP-GRN-06505 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (GRN). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
GRN Gene-specific copy number variation probes are mainly used to detect the copy number variation related to GRN genes. This product achieves the purpose of detection by hybridizing with the GRN gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Granulin Precursor |
| Gene Summary [Provided by RefSeq] |
Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
GRN |
| Location |
17q21.31 |
| Chromosome |
Chromosome17 |
| Coordinates |
This gene maps to 42422490-42430470 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-GRN-06505-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-GRN-06505-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-GRN-06505-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-GRN-06505-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-GRN-06505-AQ |
467nm |
418nm |
|
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