Gene-specific Copy Number Variation Probe-GRIA2
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| Catalog: |
CNVFP-GRIA2-06224 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (GRIA2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
GRIA2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to GRIA2 genes. This product achieves the purpose of detection by hybridizing with the GRIA2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Glutamate Ionotropic Receptor AMPA Type Subunit 2 |
| Gene Summary [Provided by RefSeq] |
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for brain function, and defective GRIA2 RNA editing at the Q/R site may be relevant to amyotrophic lateral sclerosis (ALS) etiology. Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
GRIA2 |
| Location |
4q32.1 |
| Chromosome |
Chromosome4 |
| Coordinates |
This gene maps to 158141735-158287226 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-GRIA2-06224-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-GRIA2-06224-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-GRIA2-06224-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-GRIA2-06224-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-GRIA2-06224-AQ |
467nm |
418nm |
|
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