Gene-specific Copy Number Variation Probe-GPR149
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| Catalog: |
CNVFP-GPR149-06301 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (GPR149). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
GPR149 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to GPR149 genes. This product achieves the purpose of detection by hybridizing with the GPR149 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
G Protein-coupled Receptor 149 |
| Gene Summary [Provided by RefSeq] |
This gene encodes a seven-transmembrane G protein coupled receptor (GPCR) class A family member. Although categorized as a class A GPCR, the encoded protein lacks the first two charged amino acids of the highly conserved Asp-Arg-Tyr (DRY) motif found in the third transmembrane helix of class A receptors which is important for efficient G protein-coupled signal transduction. Mice with a knockout of the orthologous gene are viable and have normal maturation of the ovarian follicle, but show enhanced fertility and ovulation. All GPCRs have a common structural architecture consisting of seven transmembrane alpha-helices interconnected by three extracellular and three intracellular loops. A general feature of GPCR signaling is agonist-induced conformational changes in the receptor, leading to activation of the heterotrimeric G proteins, which consist of the guanine nucleotide-binding G-alpha subunit and the dimeric G-beta-gamma subunits. The activated G proteins then bind to and activate numerous downstream effector proteins, which generate second messengers that mediate a broad range of cellular and physiological processes. [provided by RefSeq, Jul 2017] |
| Gene Symbol |
GPR149 |
| Location |
3q25.2 |
| Chromosome |
Chromosome3 |
| Coordinates |
This gene maps to 154055460-154147504 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-GPR149-06301-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-GPR149-06301-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-GPR149-06301-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-GPR149-06301-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-GPR149-06301-AQ |
467nm |
418nm |
|
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