Gene-specific Copy Number Variation Probe-GEN1
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| Catalog: |
CNVFP-GEN1-05987 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (GEN1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
GEN1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to GEN1 genes. This product achieves the purpose of detection by hybridizing with the GEN1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
GEN1, Holliday Junction 5' Flap Endonuclease |
| Gene Summary [Provided by RefSeq] |
This gene encodes a member of the Rad2/xeroderma pigmentosum group G nuclease family, whose members are characterized by N-terminal and internal xeroderma pigmentosum group G nuclease domains followed by helix-hairpin-helix domains and disordered C-terminal domains. The protein encoded by this gene is involved in resolution of Holliday junctions, which are intermediate four-way structures that covalently link DNA during homologous recombination and double-strand break repair. The protein resolves Holliday junctions by creating dual incisions across the junction to produce nicked duplex products that can be ligated. In addition, this protein has been found to localize to centrosomes where it has been implicated in regulation of centrosome integrity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016] |
| Gene Symbol |
GEN1 |
| Location |
2p24.2 |
| Chromosome |
Chromosome2 |
| Coordinates |
This gene maps to 17935176-17966632 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-GEN1-05987-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-GEN1-05987-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-GEN1-05987-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-GEN1-05987-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-GEN1-05987-AQ |
467nm |
418nm |
|
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