Gene-specific Copy Number Variation Probe-GDNF
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| Catalog: |
CNVFP-GDNF-05959 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (GDNF). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
GDNF Gene-specific copy number variation probes are mainly used to detect the copy number variation related to GDNF genes. This product achieves the purpose of detection by hybridizing with the GDNF gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Glial Cell Derived Neurotrophic Factor |
| Gene Summary [Provided by RefSeq] |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The recombinant form of this protein, a highly conserved neurotrophic factor, was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. This protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Mutations in this gene may be associated with Hirschsprung disease and Tourette syndrome. This gene encodes multiple protein isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Aug 2016] |
| Gene Symbol |
GDNF |
| Location |
5p13.2 |
| Chromosome |
Chromosome5 |
| Coordinates |
This gene maps to 37812778-37839782 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-GDNF-05959-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-GDNF-05959-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-GDNF-05959-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-GDNF-05959-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-GDNF-05959-AQ |
467nm |
418nm |
|
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