Gene-specific Copy Number Variation Probe-GCK
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| Catalog: |
CNVFP-GCK-05655 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (GCK). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
GCK Gene-specific copy number variation probes are mainly used to detect the copy number variation related to GCK genes. This product achieves the purpose of detection by hybridizing with the GCK gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Glucokinase |
| Gene Summary [Provided by RefSeq] |
This gene encodes a member of the hexokinase family of proteins. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. The use of multiple promoters and alternative splicing of this gene result in distinct protein isoforms that exhibit tissue-specific expression in the pancreas and liver. In the pancreas, this enzyme plays a role in glucose-stimulated insulin secretion, while in the liver, this enzyme is important in glucose uptake and conversion to glycogen. Mutations in this gene that alter enzyme activity have been associated with multiple types of diabetes and hyperinsulinemic hypoglycemia. [provided by RefSeq, Aug 2017] |
| Gene Symbol |
GCK |
| Location |
7p13 |
| Chromosome |
Chromosome7 |
| Coordinates |
This gene maps to 44183869-44229022 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-GCK-05655-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-GCK-05655-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-GCK-05655-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-GCK-05655-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-GCK-05655-AQ |
467nm |
418nm |
|
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