Gene-specific Copy Number Variation Probe-FXYD5
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| Catalog: |
CNVFP-FXYD5-05838 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (FXYD5). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
FXYD5 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to FXYD5 genes. This product achieves the purpose of detection by hybridizing with the FXYD5 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
FXYD Domain Containing Ion Transport Regulator 5 |
| Gene Summary [Provided by RefSeq] |
This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, is a glycoprotein that functions in the up-regulation of chemokine production, and it is involved in the reduction of cell adhesion via its ability to down-regulate E-cadherin. It also promotes metastasis, and has been linked to a variety of cancers. Alternative splicing results in multiple transcript variants. [RefSeq curation by Kathleen J. Sweadner, Ph.D., sweadner@helix.mgh.harvard.edu., Sep 2009] |
| Gene Symbol |
FXYD5 |
| Location |
19q13.12 |
| Chromosome |
Chromosome19 |
| Coordinates |
This gene maps to 35645624-35660788 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-FXYD5-05838-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-FXYD5-05838-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-FXYD5-05838-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-FXYD5-05838-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-FXYD5-05838-AQ |
467nm |
418nm |
|
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