Gene-specific Copy Number Variation Probe-FOLH1
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Catalog: |
CNVFP-FOLH1-05628 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (FOLH1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
FOLH1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to FOLH1 genes. This product achieves the purpose of detection by hybridizing with the FOLH1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Folate Hydrolase 1 |
Gene Summary [Provided by RefSeq] |
This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. [provided by RefSeq, Jul 2010] |
Gene Symbol |
FOLH1 |
Location |
11p11.12 |
Chromosome |
Chromosome11 |
Coordinates |
This gene maps to 49168186-49230222 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
OR
|
CNVFP-FOLH1-05628-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-FOLH1-05628-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-FOLH1-05628-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-FOLH1-05628-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-FOLH1-05628-AQ |
467nm |
418nm |
|
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