Gene-specific Copy Number Variation Probe-FMO3
Add to Cart
| Catalog: |
CNVFP-FMO3-05387 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (FMO3). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
FMO3 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to FMO3 genes. This product achieves the purpose of detection by hybridizing with the FMO3 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Flavin Containing Monooxygenase 3 |
| Gene Summary [Provided by RefSeq] |
Flavin-containing monooxygenases (FMO) are an important class of drug-metabolizing enzymes that catalyze the NADPH-dependent oxygenation of various nitrogen-,sulfur-, and phosphorous-containing xenobiotics such as therapeutic drugs, dietary compounds, pesticides, and other foreign compounds. The human FMO gene family is composed of 5 genes and multiple pseudogenes. FMO members have distinct developmental- and tissue-specific expression patterns. The expression of this FMO3 gene, the major FMO expressed in adult liver, can vary up to 20-fold between individuals. This inter-individual variation in FMO3 expression levels is likely to have significant effects on the rate at which xenobiotics are metabolised and, therefore, is of considerable interest to the pharmaceutical industry. This transmembrane protein localizes to the endoplasmic reticulum of many tissues. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Mutations in this gene cause the disorder trimethylaminuria (TMAu) which is characterized by the accumulation and excretion of unmetabolized trimethylamine and a distinctive body odor. In healthy individuals, trimethylamine is primarily converted to the non odorous trimethylamine N-oxide.[provided by RefSeq, Jan 2016] |
| Gene Symbol |
FMO3 |
| Location |
1q24.3 |
| Chromosome |
Chromosome1 |
| Coordinates |
This gene maps to 171060017-171086959 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-FMO3-05387-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-FMO3-05387-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-FMO3-05387-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-FMO3-05387-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-FMO3-05387-AQ |
467nm |
418nm |
|
Other Products
