Gene-specific Copy Number Variation Probe-FKBP4
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| Catalog: |
CNVFP-FKBP4-05459 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (FKBP4). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
FKBP4 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to FKBP4 genes. This product achieves the purpose of detection by hybridizing with the FKBP4 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
FK506 Binding Protein 4 |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes. This encoded protein is known to associate with phytanoyl-CoA alpha-hydroxylase. It can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors. This protein correlates strongly with adeno-associated virus type 2 vectors (AAV) resulting in a significant increase in AAV-mediated transgene expression in human cell lines. Thus this encoded protein is thought to have important implications for the optimal use of AAV vectors in human gene therapy. The human genome contains several non-transcribed pseudogenes similar to this gene. [provided by RefSeq, Sep 2008] |
| Gene Symbol |
FKBP4 |
| Location |
12p13.33 |
| Chromosome |
Chromosome12 |
| Coordinates |
This gene maps to 2904107-2914587 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-FKBP4-05459-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-FKBP4-05459-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-FKBP4-05459-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-FKBP4-05459-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-FKBP4-05459-AQ |
467nm |
418nm |
|
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