Gene-specific Copy Number Variation Probe-FEN1
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| Catalog: |
CNVFP-FEN1-05245 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (FEN1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
FEN1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to FEN1 genes. This product achieves the purpose of detection by hybridizing with the FEN1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Flap Structure-specific Endonuclease 1 |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap that is necessary for both binding and cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
FEN1 |
| Location |
11q12.2 |
| Chromosome |
Chromosome11 |
| Coordinates |
This gene maps to 61560108-61564714 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-FEN1-05245-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-FEN1-05245-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-FEN1-05245-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-FEN1-05245-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-FEN1-05245-AQ |
467nm |
418nm |
|
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